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Abstract #0251

Acute DKI Alterations in Mild Traumatic Brain Injury Patients with and without Eventual Symptomatic Improvement

Joseph H. Rosenberg 1 , Jiachen Zhuo 1 , Chandler R. Sours 1 , Steven Roys 1 , Elijah O. George 1 , Kathirkamanthan Shanmuganathan 1 , and Rao P. Gullapalli 1

1 Deagnostic Radiology, University of Maryland School of Medicine, Baltimore, MD, United States

DKI parameters were evaluated in mild traumatic brain injury patients. Patients were compared to controls, and patients with symptomatic improvement between sub-acute and chronic injury stages were compared to those without. Patients showed alterations in DKI parameters in the genu of the corpus callosum. Patients experiencing later symptom improvement showed DKI alterations at the acute stage distinct from those whose symptoms did not improve. Commonly affected regions were the corpus callosum body and genu and bilateral anterior corona ratiata. These DKI alterations may indicate greater acute microstructural damage to white matter tracts in those without eventual symptomatic improvement.

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