Abstract #0251
Acute DKI Alterations in Mild Traumatic Brain Injury Patients with and without Eventual Symptomatic Improvement
Joseph H. Rosenberg 1 , Jiachen Zhuo 1 , Chandler R. Sours 1 , Steven Roys 1 , Elijah O. George 1 , Kathirkamanthan Shanmuganathan 1 , and Rao P. Gullapalli 1
1
Deagnostic Radiology, University of Maryland
School of Medicine, Baltimore, MD, United States
DKI parameters were evaluated in mild traumatic brain
injury patients. Patients were compared to controls, and
patients with symptomatic improvement between sub-acute
and chronic injury stages were compared to those
without. Patients showed alterations in DKI parameters
in the genu of the corpus callosum. Patients
experiencing later symptom improvement showed DKI
alterations at the acute stage distinct from those whose
symptoms did not improve. Commonly affected regions were
the corpus callosum body and genu and bilateral anterior
corona ratiata. These DKI alterations may indicate
greater acute microstructural damage to white matter
tracts in those without eventual symptomatic
improvement.
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