Abstract #0258
Neural mechanisms of brain plasticity with cognitive training in healthy seniors
Sina Aslan 1,2 , Sandra B Chapman 2 , Jeffrey S Spence 2 , Molly Keebler 2 , Nyaz Didehbani 2 , and Hanzhang Lu 3
1
Advance MRI, LLC, Frisco, Texas, United
States,
2
Center
for BrainHealth, University of Texas at Dallas, Dallas,
Texas, United States,
3
Advanced
Imaging Research Center, University of Texas
Southwestern Medical Center, Dallas, Texas, United
States
This study investigates that engaging in complex mental
activity offer promising ways to enhance brain integrity
to promote successful cognitive aging. Using three
MRI-based measurements, i.e. pCASL MRI, fcMRI, and DTI,
we examined brain changes across three time points pre,
mid, and post-training (12-weeks) in a randomized sample
who received cognitive training versus a control group.
We found significant training-related brain state
changes at rest; specifically, (1) increases in global
and regional CBF, particularly in the default mode and
central executive networks, (2) greater connectivity in
these same networks, and (3) increased white matter
integrity in the left uncinate fasciculus.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
