Meeting Banner
Abstract #0372

Pre- and postprandial arterial and portal venous liver perfusion using selective spin labeling MRI with Look-Locker read-out

Hanke J. Schalkx 1 , Marijn van Stralen 2 , Nicky H.G.M. Peters 1 , Wouter B. Veldhuis 1 , Maarten S Van Leeuwen 1 , Josien P.W. Pluim 2 , Esben T. Petersen 1 , and Maurice A.A.J. van den Bosch 1

1 Radiology, University Medical Center, Utrecht, Netherlands, 2 Image Sciences Institute, University Medical Center, Utrecht, Netherlands

Spin labeling (SL) MRI of the liver has been performed before, but has not been done using Look-Locker readout in humans. We investigated arterial and portal SL-MRI with Look-Locker readout in healthy volunteers to improve quantification by taking regional bolus arrival times into account. Portal venous liver perfusion significantly increased after meal ingestion, while arterial liver perfusion decreased although not significantly. Postprandial portal venous perfusion change based on SL-MRI with LL readout showed fair correlation with portal venous flow changes. SL-MRI is non-invasive and could potentially contribute to diagnosis and treatment monitoring of liver diseases with elimination of contrast-related risks.

This abstract and the presentation materials are available to members only; a login is required.

Join Here