Abstract #0372
Pre- and postprandial arterial and portal venous liver perfusion using selective spin labeling MRI with Look-Locker read-out
Hanke J. Schalkx 1 , Marijn van Stralen 2 , Nicky H.G.M. Peters 1 , Wouter B. Veldhuis 1 , Maarten S Van Leeuwen 1 , Josien P.W. Pluim 2 , Esben T. Petersen 1 , and Maurice A.A.J. van den Bosch 1
1
Radiology, University Medical Center,
Utrecht, Netherlands,
2
Image
Sciences Institute, University Medical Center, Utrecht,
Netherlands
Spin labeling (SL) MRI of the liver has been performed
before, but has not been done using Look-Locker readout
in humans. We investigated arterial and portal SL-MRI
with Look-Locker readout in healthy volunteers to
improve quantification by taking regional bolus arrival
times into account. Portal venous liver perfusion
significantly increased after meal ingestion, while
arterial liver perfusion decreased although not
significantly. Postprandial portal venous perfusion
change based on SL-MRI with LL readout showed fair
correlation with portal venous flow changes. SL-MRI is
non-invasive and could potentially contribute to
diagnosis and treatment monitoring of liver diseases
with elimination of contrast-related risks.
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