Abstract #0378
Intravoxel Incoherent Motion MR Imaging shows lower pure molecular diffusion, lower diffusion fraction linked to microcirculation, and lower perfusion-related diffusion in fibrotic livers with a severity correlated manner
Yi-Xiang Wang 1 , Pu-Xuan Lu 2 , Hua Huang 2 , Feng Zhao 1 , and Jing Yuan 1
1
Dept Imaging and Interventional Radiology,
The Chinese University of Hong Kong, Shatin, NT, Hong
Kong,
2
Department
of Radiology, the Shenzhen Third People's Hospital,
Shenzhen, Guangdong, China
This current study reports the results of intravoxel
incoherent motion (IVIM)-based diffusion weighted
imaging evaluation of 17 healthy volunteers and 34 liver
fibrosis subjects. Pure molecular diffusion (D), the
fraction of the diffusion linked to microcirculation
(f), and perfusion-related diffusion (D*) were computed.
The results demonstrated all D value, f value, and D*
value were significantly lower in the fibrosis livers
compared with the healthy livers, and progressively
lower as the severity of liver fibrosis increased.
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