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Abstract #0795

PFG Filter for Oscillating Gradient Diffusion Measurements

Bibek Dhital 1 , Jochen Leupold 2 , and Valerij G. Kiselev 2

1 German Cancer Consortium (DKTK), Heidelberg, Baden, Germany, 2 Department of Diagnostic Radiology, University Medical Center Freiburg, Freiburg, Baden Wrttemberg, Germany

In this abstract we discuss application of PFG at long diffusion times and small q to discriminate between and hindered and restricted diffusion pools. We implement this as a preparation module to oscillating gradient diffusion weighted sequence. Since both the PFG and oscillating gradient waveforms are sensitive to diffusive motion, proper application of such PFG-filter requires that no cross terms exist between the two. Two sets of oscillating gradient diffusion weighted measurements on a celery stalk, one with the PFG-filter and other without. Our results confirm that in voxels containing heterogeneous regions, the PFG-filter can resolve the two compartments.

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