Abstract #0828
Non-Invasive in vivo Measurements of Inertial Forces in Muscle using Phase Contrast Magnetic Resonance Imaging
Andrew L Wentland 1 , Emily J McWalter 2 , Saikat Pal 3 , Scott L Delp 3 , and Garry E Gold 2,3
1
Medical Physics, University of
Wisconsin School of Medicine & Public Health,
Madison, WI, United States,
2
Radiology,
Stanford University, Stanford, CA, United
States,
3
Bioengineering,
Stanford University, Stanford, CA, United States
The purpose of this study was to create a novel
tool for computing muscle forces non-invasively
in vivo. Cross-sectional images of the forearms
and lower legs of healthy volunteers were
acquired with a fat/water separation technique
as well as 2D phase contrast MRI during 1 Hz
cycles of flexion/relaxation. Forces were
derived from these images. Results indicate that
this technique provides the ability to quantify
inertial forces rather than applied forces. As a
result, this technique provides the first known
method for quantifying inertial forces. This
analysis technique may be useful in evaluating
muscle pathophysiology and further developing
biomechanical models.
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