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Abstract #1004

Quantification of intragastric fat distribution using IDEAL

Dian Liu 1 , Jelena Curcic 1,2 , Andreas Steingoetter 1,2 , and Sebastian Kozerke 1

1 Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland, 2 Division of Gastroenterology and Hepatology, University of Zurich, Zurich, Switzerland

The increase in nutrition-related diseases has prompted immense efforts to understand how food systems, and in particular lipids, are sensed, processed and digested in the gastrointestinal (GI) tract. Accurate in vivo fat quantification by MRI requires modeling of all relevant chemical shift species contained in fat, and thus the acquisition of sufficient number of echo times. Objective of this work was to validate and implement hierarchical IDEAL for measuring intragastric fat distribution of lipid emulsions. Using a 6-point IDEAL approach, intragastric distribution and emptying of fat in emulsions could be assessed within a single breath hold.

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