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Abstract #1073

Diffusion-weighted imaging of prostate cancer using statistical model based on a gamma distribution

Hiroshi Shinmoto 1 , Chiharu Tamura 1 , Shigeyoshi Soga 1 , Teppei Okamura 1 , Kentaro Yamada 1 , Tatsumi Kaji 1 , and Koichi Oshio 2

1 Radiology, National Defense Medical College, Saitama, Japan, 2 Diagnostic Radiology, Keio University, School of Medicine, Tokyo, Japan

The purpose of this study was to investigate the distribution of diffusion coefficients in prostate cancer (PC) and healthy peripheral zone (PZ) using the statistical model based on a gamma distribution. Twenty-six patients with PC were included in this study. The mean and the standard deviation were significantly lower in PC than in PZ. ADC < 1.0 (%) was significantly higher in PC than in PZ and ADC > 3.0 (%) was significantly lower in PC than in PZ. The statistical model provides additional insight for DWI and allows us better correlation of diffusion signal decay and histologic findings.

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