Abstract #1094
Pulsed-continuous arterial spin labeling MRI with multiple post-labeling delay in renal cell carcinoma: clinical feasibility and initial results of a comparative study with parametric dynamic contrast-enhanced MRI
Nobuyuki Kosaka 1 , Katsuki Tsuchiyama 2 , Kazuhiro Shimizu 1 , Yasuhiro Fujiwara 3 , Tsuyoshi Matsuda 4 , Tatsuya Yamamoto 1 , Tatsuro Tsuchida 1 , Nobuyuki Oyama 2 , and Hirohiko Kimura 1
1
Department of Radiology, University of
Fukui, Eiheiji, Fukui, Japan,
2
Department
of Urology, University of Fukui, Eiheiji, Fukui, Japan,
3
Radiological
Center, University of Fukui Hospital, Eiheiji, Fukui,
Japan,
4
Global
MR Applications and Workflow, GE Healthcare Japan, Hino,
Tokyo, Japan
Pulsed-continuous arterial spin labeling MRI (pcASL)
with multiple post-labeling-delay to measure arterial
transit time-corrected tumor blood flow (ATC-TBF) in
renal cell carcinoma was performed and compared to
parametric dynamic contrast-enhanced MRI (DCE-MRI). All
image acquisitions and data post-processings were
successfully achieved in all 6 patients, and high
signals of 5 clear cell carcinomas were visually
identified. Both maximum slope and contrast enhancement
ratio correlated significantly with ATC-TBF. K
trans
,
v
e
, and IAUGC
90
@showed positive
but non-significant correlations. pcASL with multiple
PLD appears clinically feasible for measuring ATC-TBF,
which correlated with several hemodynamic parameters of
DCE-MRI.
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