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Abstract #1731

Sensitivity Assessment Comparison of Slice Accelerated Diffusion EPI vs. SSEPI for C-spine applications at 3T

Judy Rose James 1 , Peter D. Kollasch 2,3 , Blake A. Engberg 1 , Leland S. Hu 1 , Catherine Chong 4 , and Anshuman Panda 1

1 Radiology, Mayo Clinic, Scottsdale, AZ, United States, 2 Mayo Clinic, AZ, United States, 3 MR Research and Development, Siemens Medical Solutions USA, Inc, Rochester, MN, United States, 4 Collaborative Research, Mayo Clinic, Phoenix, AZ, United States

Clinical DTI in the cervical spine (C-spine) employs the single shot EPI-based Diffusion Weighted Imaging (SS-EPI-DWI) technique. Given the propensity for image distortion and low signal to noise ratio, optimization of DTI image quality often requires an increase in the number of averages, at the cost of proportionally increasing scan time. A modified SS-EPI-DWI sequence called Slice-Accelerated-Single-Shot-Spin-Echo- EPI (commonly termed as Multiband-DWI) offers improved image quality while reducing scan time and image distortion. In this study, we will evaluate C-spine image acquisitions at 3T using Multiband-DWI and SS-EPI-DWI techniques, specifically comparing 1) qualitative image quality, 2) quantitative DWI/DTI metrics, and 3) acquisition scan time.

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