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Abstract #1793

Inverse Relationship of Internal Jugular Vein Narrowing and Increased Brain Volumes is Mitigated by Age in Healthy Individuals

Chris Magnano 1,2 , Pavel Belov 1 , Jacqueline Krawiecki 1 , Steven Grisafi 1 , Jesper Hagemeier 1 , and Robert Zivadinov 1,2

1 BNAC, SUNY Buffalo, Buffalo, NY, United States, 2 MRI, Clinical & Translational Research Center, Buffalo, NY, United States

In 135 healthy controls, internal jugular vein (IJV) narrowing was found to significantly correlate with increased brain volumes, when accounting for sex and cardiovascular risk factors. This finding could be potentially indicative of edema, venous stasis, or swelling of the brain parenchyma. This relationship was lost when accounting for age. More robust correlations were found at lower cervical levels (C7/T1) than higher levels (C2/C3). This is the first study investigating the relationship between IJV narrowing and brain volumes in healthy individuals.

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