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Abstract #1794

A comparative study of two partial volume estimation methods with MP2RAGE data at 3T

Quentin Duch 1,2 , Parnesh Raniga 2,3 , Gary F. Egan 3 , Oscar Acosta 1 , Olivier Salvado 2 , Giulio Gambarota 1 , and Herv Saint-Jalmes 1

1 Universit de Rennes 1 - LTSI, Rennes, France, 2 The Australian e-Health Research Centre, CSIRO Preventative Health Flagship, CSIRO Computational Informatics, Herston, QLD, Australia, 3 Monash Biomedical Imaging, Melbourne, VIC, Australia

Partial volume (PV) effects are an unavoidable artifact in brain MRI. It may critically influence structural measurements (volumes, cortical thickness) if not taken into account. This study aims at comparing the plebiscited PV estimation technique and the proposed method on four MP2RAGE datasets. The experimental results match with the simulations and show that the plebiscited method tends to understimate GM in both types of mixtures (GM/CSF and GM/WM). This implies a global GM volume underestimation of 3.43% in average.

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