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Abstract #1885

Noninvasive Evaluation of Electrical Conductivity of the Normal Brain and Brain Tumors

Khin Khin Tha 1 , Christian Stehning 2 , Yuriko Suzuki 3 , Ulrich Katscher 2 , Jochen Keupp 2 , Ken Kazumata 1 , Shunsuke Terasaka 1 , Marc Van Cauteren 3 , Kohsuke Kudo 1 , and Hiroki Shirato 1

1 Hokkaido University Graduate School of Medicine, Sapporo, Japan, 2 Philips Technologie GmbH, Germany, 3 Philips Electronics, Japan

This study evaluated the repeatability of noninvasive electrical conductivity measurements by electric properties tomography (EPT) and the conductivity values of the normal intracranial compartments, normal-appearing brain parenchyma and intra-axial brain tumors, in 1 normal subject and 25 brain tumor patients. The results revealed high repeatability of the measurements, significantly different conductivity metrics between the tumors and adjacent normal-appearing brain parenchyma, and possible differentiation of WHO grade IV tumors from the other tumors. EPT provides information about the tissuesf electrical conductivity noninvasively and in vivo, and can become a tool for diagnosis and monitoring of the brain tumors.

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