Noninvasive Evaluation of Electrical Conductivity of the Normal Brain and Brain Tumors
Khin Khin Tha 1 , Christian Stehning 2 , Yuriko Suzuki 3 , Ulrich Katscher 2 , Jochen Keupp 2 , Ken Kazumata 1 , Shunsuke Terasaka 1 , Marc Van Cauteren 3 , Kohsuke Kudo 1 , and Hiroki Shirato 1
Hokkaido University Graduate School of
Medicine, Sapporo, Japan,
Technologie GmbH, Germany,
This study evaluated the repeatability of noninvasive
electrical conductivity measurements by electric
properties tomography (EPT) and the conductivity values
of the normal intracranial compartments,
normal-appearing brain parenchyma and intra-axial brain
tumors, in 1 normal subject and 25 brain tumor patients.
The results revealed high repeatability of the
measurements, significantly different conductivity
metrics between the tumors and adjacent normal-appearing
brain parenchyma, and possible differentiation of WHO
grade IV tumors from the other tumors. EPT provides
information about the tissuesf electrical conductivity
noninvasively and in vivo, and can become a tool for
diagnosis and monitoring of the brain tumors.
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