Abstract #1892
Preliminary study on structural brain network topology in chronic knee OA pain
Yue Xing 1,2 , Hamza Alshuft 1,2 , and Dorothee Auer 1,2
1
Radiological Sciences, University of
Nottingham, Nottingham, United Kingdom,
2
Arthritis
Research UK Pain Centre, University of Nottingham,
Nottinghamshire, United Kingdom
Graph theory combining MRI techniques enables a
non-invasive description of structural and functional
network topology in human brain. Despite the recent
explosion of studies on functional brain network and
anatomical connectivity provided by diffusion MRI,
little is known about the structural architecture in
patients with primary nociceptive disorders, which may
cause reconfiguration of the underlying brain
organisation. We measured cortical thickness of more
precise localization of sulco-gyral regions on patients
with chronic pain due to knee osteoarthritis and healthy
controls. By applying graph theory analysis, we present
a preliminary morphometric signature of knee
osteoarthritis pain.
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