Abstract #1899
Correlations between diffusion-weighted and clinical parameters in uncompensated vestibular patients - a pilot study.
Angelique Van Ombergen 1 , Ben Jeurissen 2 , Floris Vanhevel 3 , Wim Van Hecke 4 , Vincent Van Rompaey 5 , Jan Sijbers 2 , Stefan Sunaert 6 , Paul Parizel 3 , Paul van de Heyning 5 , and Floris Wuyts 1
1
Antwerp University Research center for
Equilibrium and Aerospace, University of Antwerp,
Antwerp, Belgium,
2
Vision
Lab, Department of Physics, University of Antwerp,
Antwerp, Belgium,
3
Department
of Radiology, Antwerp University Hospital & University
of Antwerp, Antwerp, Belgium,
4
icoMetrix,
Leuven, Belgium,
5
Department
of Otorhinolaryngology and Head and Neck Surgery,
Antwerp University Hospital & University of Antwerp,
Belgium,
6
Department
of Radiology, University Hospital of the Catholic
University of Leuven, Leuven, Belgium
Correlations between diffusion and clinical vestibular
parameters in uncompensated vestibular patients and
healthy controls were investigated. Multi-shell high
angular resolution diffusion weighted data were acquired
and tractography was performed. We found multiple
significant correlations between diffusion parameters in
several vestibular-related brain regions and clinical
parameters. Thus, this pilot study shows that quantities
derived from diffusion-weighted imaging appear to be
correlated with several clinical parameters from
vestibular testing. This suggests that the cause of the
symptoms of unresolved continuous vertigo is probably
more situated at the central level than at the
peripheral level.
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