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Abstract #1968

Boys with Comorbid ADHD and RD Show Increasing Disengagement with Age During a Sustained Attention Task

Brianne Mohl 1 , Dhruman D. Goradia 1 , Dalal Khatib 1 , Usha Rajan 1 , Arthur L. Robin 1 , David R. Rosenberg 1 , Noa Ofen 1,2 , Joseph E. Casey 3 , Vaibhav A. Diwadkar 1 , and Jeffrey A. Stanley 1

1 Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, Michigan, United States, 2 Merrill Palmer Skillman Institute, Wayne State University, Detroit, Michigan, United States, 3 Psychology, University of Windsor, Windsor, Ontario, Canada

ADHD commonly occurs with a reading disability (RD); inattention has been linked with poorer reading measures in ADHD. However, the neural basis of the association has yet to be investigated. Age interactions and main effects of diagnosis were modeled for functional activations in ADHD+RD, ADHD-RD, and controls during a sustained attention fMRI task. Results suggest that developmental patterns may be similar in ADHD subgroups compared to controls, but the degree of hypoactivation in attention-related areas is significantly worse in ADHD+RD.

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