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Abstract #2042

Predicting Final Infarct Volume at One Week Post Ischemic Stroke: Recanalization and Baseline Infarct Volume are Important Parameters for Early Infarct Estimation

Mark Krongold 1,2 , Mohammed Almekhlafi 1,2 , Andrew Demchuck 1,3 , Richard Frayne 1,2 , and Armin Eilaghi 1,2

1 Department of Radiology and Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada, 2 Seaman Family MR Centre, Foothills Medical Centre, Calgary, Alberta, Canada, 3 Calgary Stroke Program, Foothills Medical Centre, Calgary, Alberta, Canada

Our goal was to characterize infarct volume evolution over time with focus on the first 30 days post stroke. We screened 964 ischemic stroke patients and included 59 patients who had baseline DWI infarction and ≥2 FLAIR follow up imaging sessions. We show that the final infarct volume can be predicted after the first week. Recanalization status and baseline infarct volume significantly effect infarct expansion pattern and infarct volume size. These findings can potentially maximize recruitment in clinical trials, decrease needed follow up imaging sessions, and improve stroke management.

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