Abstract #2043
IVIM Perfusion Fraction in Acute Stroke: Initial Clinical Experience
Christian Federau 1 , Suna Sumer 2 , Fabio Becce 1 , Kieran O'Brien 3 , Reto Meuli 1 , and Max Wintermark 2
1
Radiology, CHUV, Lausanne, Vaud,
Switzerland,
2
Neuroradiology
Division, Department of Radiology, University of
Virginia, Charlottesville, Virginia, United States,
3
Center
for Biomedical Imaging (CIBM), University of Geneva,
Geneva, Switzerland
In the setting of acute ischemic stroke, currently used
perfusion methods (DSC and CTP) may fail to properly
take into account leptomeningeal collateral blood flow
supply, which is essential for clinical prognosis.
Perfusion measurement using IVIM might theoretically
solve this issue, as it is thought to be mainly
dependent on the local microvascular perfusion. We
present our initial clinical experience in 17 cases of
acute brain strokes (< 6 days), demonstrating that the
perfusion fraction f is significantly reduced in the
infarcted area.
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