Abstract #2053
Comparison of Susceptibility-Weighted-Imaging determined vessel diameters to histological measures
Gnther Grabner 1 , Assunta Dal-Bianco 2 , Hans Lassmann 3 , Siegfried Trattnig 1 , and Simon Hametner 3
1
MR Centre of Excellence, Department of
Biomedical Imaging und Image-guided Therapy, Medical
University of Vienna, Vienna, Austria,
2
Department
of Neurology, Medical University of Vienna, Vienna,
Austria,
3
Center
for Brain Research, Medical University of Vienna,
Vienna, Austria
Susceptibility-Weighted-Imaging allows high resolution
imaging of the venous system. However, the real size of
the imaged veins remains unknown. The purpose of this
study was to determine the relation between apparent SWI
vessel sizes and real vessel diameters measured on
histological tissue. Two in-vitro SWI acquisitions were
performed, one on a healthy and one on a multiple
sclerosis brain. Furthermore we compared the SWI
enlargement factor in healthy brain tissue to the MS
brain. Results indicate an SWI enlargement factor of
about 3.7 for vessels with a histological diameter below
100 m independently from disease status.
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