Abstract #2134
Standard compared to optimized mDIXON liver fat fraction imaging
Jurgen H. Runge 1 , Bram F. Coolen 1 , Edmond Balidemaj 2 , Ulrich H. Beuers 3 , Aart J. Nederveen 1 , and Jaap Stoker 1
1
Radiology, Academic Medical Center,
Amsterdam, Netherlands,
2
Radiotherapy,
Academic Medical Center, Amsterdam, Netherlands,
3
Gastroenterology
& Hepatology, Academic Medical Center, Amsterdam,
Netherlands
Standard mDIXON fat-water imaging can be used to
reconstruct quantitative fat fraction maps. However, a
non-zero intercept of circa 4% is reported upon in
recent literature. We optimized the mDIXON protocol by
increasing the TR to reduce T1-weighting and by choosing
more echoes with asymmetric TEs for a higher NSA. We
investigated in phantoms and patients whether this
optimized protocol increased accuracy in comparison to
1
H-MRS.
In phantoms, the non-zero intercept was resolved, but
not in patients. Differences in T1 values of phantoms
and tissue may explain why the issue remained for in
vivo measurements.
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