Abstract #2276
Early Detection Of Smoking-Induced Pulmonary Alterations Using Hyperpolarized 3 He MRI Derived Alveolar Partial Pressure of Oxygen
Hooman Hamedani 1 , Stephen J. Kadlecek 1 , Masaru Ishii 2 , Yi Xin 1 , Hoora Shaghaghi 1 , Biao Han 1 , Sarmad Siddiqui 1 , Sarah Zarrin 3 , Milton Rossman 1 , and Rahim R. Rizi 1
1
University of Pennsylvania, Philadelphia,
PA, United States,
2
Johns
Hopkins University, Merryland, United States,
3
University
of Pennsylvania, PA, United States
While hyperpolarized (HP) gas MRI has been used to
estimate alveolar oxygen tension (
p
A
O
2
)
[1], it has not been systematically compared to Gold
standard to assess its potential for monitoring disease
progression and response to new therapies. In this work,
we compare imaged
p
A
O
2
to
data produced via pulmonary function test, six-minute
walk test, and St.-George Questionnaire.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
