Abstract #2280
Two Dimensional Radial Pulmonary Ultra-short time 1 H MRI: Reproducibility in COPD and Bronchiectasis
Khadija Sheikh 1,2 , Weijing Ma 1,2 , Fumin Guo 1,3 , Sarah Svenningsen 1,2 , Terry M Peters 1,2 , Harvey O Coxson 4 , David G McCormack 5 , Roya Etemad-Rezai 6 , and Grace Parraga 1,2
1
Imaging Research Laboratories, Robarts
Research Institute, London, Ontario, Canada,
2
Department
of Medical Biophysics, The University of Western
Ontario, London, Ontario, Canada,
3
Graduate
Program in Biomedical Engineering, The University of
Western Ontario, London, Ontario, Canada,
4
Department
of Radiology, University of British Columbia, Vancouver,
British Columbia, Canada,
5
Department
of Medicine, The University of Western Ontario, London,
Ontario, Canada,
6
Department
of Medical Imaging, The University of Western Ontario,
London, Ontario, Canada
Ultra-short echo-time
1
H
MRI provides pulmonary
1
H
signal intensity (SI) measurements of tissue density.
The objective of this study was to evaluate three-week
reproducibility of
1
H
UTE MRI SI in subjects with bronchiectasis and chronic
bronchitis/chronic obstructive pulmonary disease (COPD)
and compare with
3
He
MRI measurements of apparent diffusion coefficients
(ADC). This is the first evaluation of
1
H
UTE SI reproducibility in bronchiectasis and COPD
subjects and there were high Pearson correlation
coefficients, relatively low COV and high ICC;
reproducibility was high and similar to
3
He
ADC reproducibility in the same subjects.
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