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Abstract #2293

A Preliminary Variability Study Of Hyperpolarized 3He Specific Ventilation In Human

Hooman Hamedani 1 , Stephen Kadlecek 1 , Masaru Ishii 2 , Yi Xin 1 , Hoora Shaghaghi 1 , Biao Han 1 , Sarmad Siddiqui 1 , Milton Rossman 1 , and Rahim R. Rizi 1

1 University of Pennsylvania, Philadelphia, PA, United States, 2 Johns Hopkins University, Merryland, United States

Regional analysis of lung ventilation is facilitated through multi-breath Hyperpolarized gas (HP) MRI, a technique that quantifies the Specific Ventilation (SV) in parenchyma. This work presents the first preliminary short- and long-term variability of SV-MRI, and compares the imaging variability to that of pulmonary function tests (PFT).

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