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Abstract #2671

The role of fronto-parietal networks in mental imagery

Henrietta Howells 1 , Marco Catani 1 , Flavio Dell'Acqua 2,3 , Anoushka Leslie 2 , Andrew Simmons 2 , Declan G. Murphy 1 , and Michel Thiebaut de Schotten 1

1 Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, London, United Kingdom, 2 Department of Neuroimaging, Institute of Psychiatry, London, United Kingdom, 3 NIHR Biomedical Research Centre for Mental Health at SLAM NHS Foundation Trust, Institute of Psychiatry, London, United Kingdom

When comparing two identical objects oriented differently, subjects perform a mental rotation of one object until it is congruent with the other. A recent diffusion tractography study revealed a correlation between right-lateralisation of a fronto-parietal pathway, the second branch of the superior longitudinal fasciculus (SLF II), and performance in certain visuo-spatial tasks. It is unknown whether this pathway is also involved in mental rotation. Using spherical deconvolution tractography, we assessed this correlation in a group of 25 healthy subjects. Our results confirmed lateralisation of this tract is associated with mental rotation performance.

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