Abstract #2679
Double-Pulsed-Field-Gradient MRI at long mixing time of global hypoxia
Darya Morozov 1 , Debbie Anaby 1 , and Yoram Cohen 1,2
1
School of Chemistry, The Raymond and Beverly
Sackler Faculty of Exact Science, Tel-Aviv University,
Tel-Aviv, Ramat-Aviv, Israel,
2
Sagol
School of Neurosciences, Tel-Aviv University, Tel-Aviv,
Ramat-Aviv, Israel
Diffusion weighted MRI and DTI, have been extensively
used to study pathologies and to perform non-invasive in
vivo tractography of the CNS. However, the ADC, FA and
MD extracted from DWI and DTI experiments have limited
sensitivity and specificity to structural changes.
Therefore there is a constant need to develop new
potential methods to provide more specific
microstructural indices. In the present work we study
the effect of global hypoxia on the indices extracted
from angular d-PFG MRI at a long mixing time and compare
them with the changes observed in the FA and MD obtained
from DTI.
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