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Abstract #2805

Quantification of Dendritic Cells entering the Lymph Nodes in Mice using 19-F MRI

Conrad Steven Martin 1 , Min-Chi Ku 1 , Stefano Lepore 1 , Helmar Waiczies 1,2 , Andreas Pohlmann 1 , Jan Hentschel 1 , Matthias Dieringer 1,2 , Thoralf Niendorf 1,2 , and Sonia Waiczies 1,3

1 Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrck Center for Molecular Medicine, Berlin-Buch, Berlin, Germany, 2 MRI.TOOLS GmbH, Berlin, Germany, Berlin-Buch, Berlin, Germany, 3 Experimental and Clinical Research Center, Berlin, Germany, Berlin-Buch, Berlin, Germany

19F MRI is used to track the movement of dendritic cells labeled with 19F nanoparticles in their progression through the lymphatic system in the hindquarters of mice. Specific quantitative and temporal data is collected by the use of Point resolved 19F spectroscopy. This has significant implications in human dendritic cell treatments.

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