Abstract #2805
Quantification of Dendritic Cells entering the Lymph Nodes in Mice using 19-F MRI
Conrad Steven Martin 1 , Min-Chi Ku 1 , Stefano Lepore 1 , Helmar Waiczies 1,2 , Andreas Pohlmann 1 , Jan Hentschel 1 , Matthias Dieringer 1,2 , Thoralf Niendorf 1,2 , and Sonia Waiczies 1,3
1
Berlin Ultrahigh Field Facility (B.U.F.F.),
Max Delbrck Center for Molecular Medicine, Berlin-Buch,
Berlin, Germany,
2
MRI.TOOLS
GmbH, Berlin, Germany, Berlin-Buch, Berlin, Germany,
3
Experimental
and Clinical Research Center, Berlin, Germany,
Berlin-Buch, Berlin, Germany
19F MRI is used to track the movement of dendritic cells
labeled with 19F nanoparticles in their progression
through the lymphatic system in the hindquarters of
mice. Specific quantitative and temporal data is
collected by the use of Point resolved 19F spectroscopy.
This has significant implications in human dendritic
cell treatments.
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