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Abstract #3228

Comparison of marketed Gadolinium-based Contrast Agents Relaxivities on Clinical MR scanner at 1.5T, 3T and 7T in water and plasma for a large range of physiological concentrations

Alexandre Vignaud 1 , Xavier Violas 2 , Alain Rahmouni 3 , Philippe Robert 2 , and Alexis Amadon 1

1 UNIRS/NeuroSpin/I2BM/DSV, CEA, Gif Sur Yvette, France, 2 Experimental Imaging, Guerbet Group, Aulnay Sous Bois, France, 3 Imagerie Mdicale Service, Henri Mondor Albert Chenevier group, AP-HP, Creteil, France

Several papers reported contrast agent (CA) relaxivity measurements at several clinical magnetic fields. None have investigated them on a large physiologically relevant range including first pass equivalent concentrations. Thus B1 and B0 heterogeneities make this data difficult to extract at Ultra High Field (UHF). In this work, using state of the art relaxometry methods, we measured r1 and r2 as a function of B0 (1.5, 3 and 7T) for a large CA concentration window

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