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Abstract #3302

Steady-state pulsed Chemical Exchange Saturation Transfer Imaging of creatine in human calf muscle followed by spillover correction evaluation

Eugenia Rerich 1 , Moritz Zaiss 1 , and Peter Bachert 1

1 Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Baden-Wrttemberg, Germany

In skeletal muscle endogenous chemical exchange saturation transfer (CEST) effects are influenced by direct water saturation and magnetization transfer (MT) effects. In this study we present a method which corrects the CEST data from spillover and apply it to in vivo data of human calf muscle. The results are compared with the more common evaluation method - the asymmetry analysis of the Z-spectrum.

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