Steady-state pulsed Chemical Exchange Saturation Transfer Imaging of creatine in human calf muscle followed by spillover correction evaluation
Eugenia Rerich 1 , Moritz Zaiss 1 , and Peter Bachert 1
Medical Physics in Radiology, German Cancer
Research Center, Heidelberg, Baden-Wrttemberg, Germany
In skeletal muscle endogenous chemical exchange
saturation transfer (CEST) effects are influenced by
direct water saturation and magnetization transfer (MT)
effects. In this study we present a method which
corrects the CEST data from spillover and apply it to in
vivo data of human calf muscle. The results are compared
with the more common evaluation method - the asymmetry
analysis of the Z-spectrum.
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