B 1 -correction of isolated, spillover-corrected CEST-effects at 7 T

The in vivo images of isolated CEST-effects aquired in wholebody scanners at ultra-high fields usually suffer from a strong spatial dependence. This is due to the influence of the rf amplitude (B ₁ ) on the effects and B ₁ inhomogeneities in the large FOV. It is shown that the acquisition of three CEST-images at different B ₁ -amplitudes yield homogeneous APT and NOE maps when using the inverse metric MTR _Rex for spillover correction.

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