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Abstract #3303

B 1 -correction of isolated, spillover-corrected CEST-effects at 7 T

Johannes Windschuh 1 , Moritz Zaiss 1 , Jan-Eric Meissner 1 , and Peter Bachert 1

1 Medical Physics in Radiology, German Cancer Research Center (DFKZ), Heidelberg, Baden-Wrttemberg, Germany

The in vivo images of isolated CEST-effects aquired in wholebody scanners at ultra-high fields usually suffer from a strong spatial dependence. This is due to the influence of the rf amplitude (B 1 ) on the effects and B 1 inhomogeneities in the large FOV. It is shown that the acquisition of three CEST-images at different B 1 -amplitudes yield homogeneous APT and NOE maps when using the inverse metric MTR Rex for spillover correction.

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