Abstract #3393
Rapid and robust whole brain myelin water mapping in 6.5 minutes: Validation and clinical feasibility
Thanh D. Nguyen 1 , Kofi Deh 1 , Ashish Raj 1 , Susan A. Gauthier 2 , and Yi Wang 1
1
Radiology, Weill Cornell Medical College,
New York, NY, United States,
2
Neurology
and Neuroscience, Weill Cornell Medical College, New
York, NY, United States
Whole brain myelin water fraction (MWF) imaging is
highly desired but currently is too time-consuming to be
useful clinically, with acquisition times exceeding 10
minutes and processing times still on the order of
hours. The purpose of this study is to develop and
optimize a rapid and robust whole brain MWF mapping
protocol for routine clinical use at 3T with 6.5 min
acquisition and 15 min processing time. Results in
healthy controls and MS patients demonstrate the
feasibility of our approach.
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