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Abstract #3450

Magnetization Transfer from Inhomogeneously Broadened Lines (ihMT): Improved SC Imaging using ECG Synchronization

Olivier M. Girard 1 , Virginie Callot 1 , Benjamin Robert 2 , Novena Rangwala 3 , Patrick J. Cozzone 1 , David C. Alsop 3 , and Guillaume Duhamel 1

1 CRMBM, UMR 7339 CNRS-AMU, Aix-Marseille Universit, Marseille, France, 2 Siemens Healthcare, Saint-Denis, France, 3 Radiology Department, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States

Inhomogeneous magnetization transfer (ihMT) imaging has been proposed as a new method for white matter imaging. The signal is specific to myelinated tissues and offers unique opportunity for CNS imaging. One challenge for spinal cord (SC) imaging is the pulsatility of the CSF that induces motion around the cord. This can have dramatic effect on the image quality and triggering options have to be considered. This study addresses this problem and proposes a methodology based on ECG synchronization and retrospective data filtering for fast acquisition of the SC ihMT signal, free of CSF pulsatility artifacts.

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