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Abstract #3518

The additively deactivated regions during a motor task in intracranial tumor patients show modulations of functional connectivity within the default mode network

Geon-Ho Jahng 1 , Seung Hwan Lee 2 , Chang-Woo Ryu 1 , Jun Seok Koh 2 , Dal-Mo Yang 1 , Kyung-Nam Ryu 3 , Dong-Wook Sung 3 , and Woo-Suk Choi 3

1 Radiology, Kyung Hee University Hospital at Gangdong, Seoul, Korea, 2 Stroke and Neurological Disorders Center, Kyung Hee University Hospital at Gangdong, Seoul, Korea, 3 Radiology, Kyung Hee University Hospital, Seoul, Korea

The default mode network (DMN) region is compatible with task-induced deactivation regions in the study of functional imaging data. Only a few studies investigated alterations of the default mode network or deactivations in patients with intracranial lesions. To investigate the alterations of the motor deactivation regions in patients with intracranial lesions compared with the normal status of brain, motor-tasked fMRI data obtained from twenty-seven patients with intracranial lesions were analyzed. There were widespread deactivations in response to the right and left motor tasks. In addition, there were 10 patients who exhibited additive motor task-induced deactivated regions.

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