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Abstract #3531

Airflow modulation due to the cardiac cycle in healthy subjects

Guilhem Jean Collier 1 , Helen Marshall 1 , and Jim Wild 1

1 Academic Radiology, University of Sheffield, Sheffield, United Kingdom

In this work, dynamic acquisition of hyperpolarized 3 He ventilation images was combined with phase contrast velocimetry sequences to assess airflow modulation due to the cardiac cycle during inspiration in healthy subjects. The results show opposite flow oscillations at the heartbeat frequency between the left lower lobe and all other lobes, suggesting that the movement of the heart is influencing the airflow pattern in the lungs.

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