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Abstract #3591

Quantification of liver steatosis in morbidly obese patients: comparative performance of low-field open MRI and Steatotest

Philippe Garteiser 1 , Sabrina Doblas 1 , Gaspard D'Assignies 2 , Doryssema Tchatat 3,4 , Simon Msika 5 , Muriel Coupaye 6 , Pierre Bedossa 1,7 , Valrie Vilgrain 1,8 , Elisabeth Dion 9 , Pauline Jouet 10 , and Bernard E Van Beers 1,8

1 CRB3, INSERM, Paris, 75018, France, 2 Radiology department, Hpital Beaujon, AP-HP, Clichy, France, 3 Groupement hospitalier Paris Nord, AP-HP, Colombes, France, 4 Hepato-gastroenterology department, Hpital Louis Mourier, AP-HP, Colombes, France, 5 Visceral Surgery department, Hpital Louis Mourier, AP-HP, Colombes, France, 6 Endocrinology Department, Hpital Louis Mourier, AP-HP, Colombes, France, 7 Anatomo-pathology Department, Hpital Beaujon, AP-HP, Clichy, France, 8 Radiology Department, Hpital Beaujon, AP-HP, Clichy, France, 9 Radiology Department, Hpital Louis Mourier, AP-HP, Colombes, France, 10 Hepato-gastroenterology Department, Hpital Louis Mourier, AP-HP, Colombes, France

Quantification of intrahepatic fat represents an important challenge in disease management for morbidly obese patients. Liver biopsy is often problematic with associated risks and limited volume of coverage. Alternate techniques include serum tests such as Steatotest and MRI fat quantification. Moreover, obese patients are often difficult to examine in conventional MRI systems and may require examinations in open magnets at low field strengths. In this report, using histopathological analyses of liver biopsies as gold standard, the diagnostic performance of 1.0T open field MR fat quantification was found to significantly outperform the serum marker Steatotest in the determination of hepatic steatosis.

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