Abstract #3591
Quantification of liver steatosis in morbidly obese patients: comparative performance of low-field open MRI and Steatotest
Philippe Garteiser 1 , Sabrina Doblas 1 , Gaspard D'Assignies 2 , Doryssema Tchatat 3,4 , Simon Msika 5 , Muriel Coupaye 6 , Pierre Bedossa 1,7 , Valrie Vilgrain 1,8 , Elisabeth Dion 9 , Pauline Jouet 10 , and Bernard E Van Beers 1,8
1
CRB3, INSERM, Paris, 75018, France,
2
Radiology
department, Hpital Beaujon, AP-HP, Clichy, France,
3
Groupement
hospitalier Paris Nord, AP-HP, Colombes, France,
4
Hepato-gastroenterology
department, Hpital Louis Mourier, AP-HP, Colombes,
France,
5
Visceral
Surgery department, Hpital Louis Mourier, AP-HP,
Colombes, France,
6
Endocrinology
Department, Hpital Louis Mourier, AP-HP, Colombes,
France,
7
Anatomo-pathology
Department, Hpital Beaujon, AP-HP, Clichy, France,
8
Radiology
Department, Hpital Beaujon, AP-HP, Clichy, France,
9
Radiology
Department, Hpital Louis Mourier, AP-HP, Colombes,
France,
10
Hepato-gastroenterology Department,
Hpital Louis Mourier, AP-HP, Colombes, France
Quantification of intrahepatic fat represents an
important challenge in disease management for morbidly
obese patients. Liver biopsy is often problematic with
associated risks and limited volume of coverage.
Alternate techniques include serum tests such as
Steatotest and MRI fat quantification. Moreover, obese
patients are often difficult to examine in conventional
MRI systems and may require examinations in open magnets
at low field strengths. In this report, using
histopathological analyses of liver biopsies as gold
standard, the diagnostic performance of 1.0T open field
MR fat quantification was found to significantly
outperform the serum marker Steatotest in the
determination of hepatic steatosis.
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