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Abstract #3619

Geometric Distortion in Diffusion-Weighted MR Imaging of the Prostate Contributing Factors and Strategies for Improvement

Francisco Donato Jr 1 , Daniel N. Costa 1 , Qing Yuan 1 , Neil M. Rofsky 1 , Robert E. Lenkinski 1 , and Ivan Pedrosa 1

1 UT Southwestern Medical Center, Dallas, TX, United States

This study is the first investigation assessing parameters that may influence geometric distortion on DWI of the prostate. We explored the causes and degree of geometric distortion observed in DWI of the prostate and assessed different acquisition strategies to mitigate deformation. The magnitude of distortion was assessed in patients and the effects of phase-encoding direction, receiver bandwidth, and parallel imaging were assessed in a prostate phantom on two different 3T MRI scanners from different manufacturers. We found that distortion occurs in the phase-encoding direction, and is less pronounced when higher bandwidth or parallel imaging is used.

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