Abstract #3786
Sleep and Wakefulness Affect GABA Levels in the Dorsolateral Prefrontal Cortex
Luke Y.-J. Wang 1,2 , Sai K. Merugumala 2 , Huijun Liao 2 , and Alexander P. Lin 2
1
Department of Anesthesiology, Perioperative
and Pain Medicine, Boston Children's Hospital and
Harvard Medical School, Boston, MA, United States,
2
Department
of Radiology, Brigham and Women's Hospital and Harvard
Medical School, Boston, MA, United States
Sleep and wakefulness are a complex yet distinct
physiological states. However, they are not generally
controlled for during brain spectroscopy. We report
higher detected levels of GABA during sleep, compared to
a controlled wakeful state.
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