Abstract #3796
Robust Single-Shot Hyperpolarized 13 C Spectroscopic Imaging Utilizing Incoherent k-t spiral Sampling and Low-Rank Matrix Completion
Jeremy W Gordon 1 , Sean B Fain 1,2 , David J Niles 1 , and Kevin M Johnson 1,2
1
Medical Physics, University of
Wisconsin-Madison, Madison, WI, United States,
2
Radiology,
University of Wisconsin-Madison, Madison, WI, United
States
Joint spatial-spectral reconstruction enables highly
accelerated
13
C
spectroscopic imaging but requires high performance
gradients to optimally sample k-t space. However,
temporal correlations between adjacent timeframes can be
exploited by permuting or shifting the TE to reduce
gradient requirements while still sampling k-t space
sufficiently. Simulations and in-vivo results indicate
that by permuting the k-t trajectory via pseudorandom
TEs and incorporating low-rank regularization, temporal
correlations across timeframes can be incorporated to
improve the conditioning of the encoding matrix and
reduce noise in low signal metabolite images. The
proposed framework reduces gradient requirements and may
enable k-t spiral sampling on clinical platforms.
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