Comparison of standardized uptake values in normal structures and breast cancer metastases using PET/CT and PET/MRI

Validation of MR attenuation correction (MRAC) is required for comparison of SUVs derived from PET/CT with those derived from PET/MRI. The current study demonstrates that SUVmax generated from MRAC correlates well with SUVmax generated from PET/CT for normal structures and breast cancer metastases, and can thus be used for quantification of FDG activity. Interestingly, the metabolic activity of breast cancer metastases during the interval between PET/CT and PET/MRI differed depending on the site of spread. Further investigation is needed to evaluate the potential role of SUV measurements in tailoring imaging protocols to the metabolic activity of organ-specific metastases.

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