Accelerated time-resolved Time-Of-Flight Magnetic Resonance Angiography in Mice Models

Anatomical and functional Time-Of-Flight (TOF) Magnetic Resonance Angiography (MRA) is a powerful tool to investigate vascular function in healthy and diseased small animal models. Nevertheless, this technique can require relatively long acquisition times. The goal of this study was to develop an accelerating strategy to improve blood flow visualisation in mice using a cine-3D echo-planar imaging sequence. This method was applied at 7T in mice to investigate carotid arteries and allowed to divide acquisition times by three compared with the previous functional TOF MRA method using a simple gradient echo sequence.

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