Abstract #4419
NMR characterization of cylinder radii distributions using a SHORE-based regularization method
Gonzalo Sanguinetti 1 , Matt G Hall 2 , Daniel C Alexander 2 , and Rachid Deriche 1
1
Athena Project-Team, INRIA, Sophia-Antipolis,
France,
2
Centre
for Medical Image Computing, Department of Computer
Science, University College London, London, United
Kingdom
We are interested in retrieving information about the
axon diameter distributions in white matter fiber
bundles using NMR, which are commonly modelled as
ensembles of parallel cylinders. We add regularization
to the 1D-SHORE basis which results in more stable
characterization of diameter distributions. To validate
the method, we simulate NMR signals using the open
source toolkit CAMINO. The results illustrate the
enhanced estimation accuracy given by the regularization
and provide an alternative validation of the SHORE based
method.
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