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Abstract #4482

Moderate protein content does not influence on DWI-thermometry: Temperature-controlled Artificial CSF phantom study

Koji Sakai 1 , Ryusuke Nakai 1 , Kei Yamada 2 , Jun Tazoe 2 , Kentaro Aakazawa 2 , and Naozo Sugimoto 1

1 Kyoto University, Kyoto, Kyoto, Japan, 2 Kyoto Prefectural University of Medicine, Kyoto, Japan

Among MR thermometry, the most clinically applicable may be the post processing of diffusion-weighted images (DWI). However, this DWI-based method might be influenced by the composition of CSF, which can strongly affect its viscosity and diffusivity. The purpose of this study was to investigate the influence of protein content on DWI thermometry by using temperature-controlled artificial CSF (ACSF). The results of DWI thermometry were not influenced by the protein content in the range of 0.0 to 8.01 mg/ml (approximately 40 times protein content of normal adult) at near body temperature.

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