Abstract #4610
Longitudinal TBSS study of preterm and at term newborns
Paola Scifo 1 , Elisa Marchetta 2,3 , Silvia Pontesilli 2 , Elisa Scola 2 , Antonella Poloniato 4 , Graziano Barbera 4 , Antonella Iadanza 2 , Andrea Falini 2,5 , and Cristina Baldoli 2
1
Nuclear Medicine, Ospedale San Raffaele,
Milan, -, Italy,
2
Neuroradiology,
Ospedale San Raffaele, Milan, -, Italy,
3
Univerist
degli Studi di Milano Bicocca, Milano, -, Italy,
4
Pediatric
Department, Ospedale San Raffaele, Milan, -, Italy,
5
Universit
Vita-Salute San Raffaele, Milan, -, Italy
Brain maturation in the early ages of life is
characterized by crucial microstructural changes. This
work aims to study the different development of White
Matter in pre-term newborns with respect to those born
at term, by using TBSS for the statistical comparison of
DTI FA and MD maps acquired on a 3T scanner. The results
show an advanced brain maturation in term vs preterm
infants at 40 weeks PMA and a progressive maturation of
preterm brains in the three ages of acquisition,
demonstrating the feasibility of TBSS analysis on DTI
data for the evaluation of myelination process.
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