Abstract #4627
Effects of craniosynostosis on cerebral blood flow
Dustin K Ragan 1 , Gary Skolnick 2 , Jose A Pineda 1 , Matthew D Smyth 3 , and Kamlesh Babulal Patel 2
1
Department of Pediatrics, Washington
University School of Medicine, St. Louis, MO, United
States,
2
Department
of Surgery, Washington University School of Medicine,
St. Louis, MO, United States,
3
Department
of Neurosurgery, Washington University School of
Medicine, St. Louis, MO, United States
Craniosynostosis is associated with elevated ICP,
however its physiological effects are largely unknown.
We studied the effects of craniosynostosis on cerebral
perfusion using pseudocontinuous ASL. Focal regions of
apparent hyperemia were detected, suggesting either
metabolic abnormalities or a decrease in CSF space.
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