Abstract #4709
Widespread brain changes in patients with advanced glaucoma
Antonio Giorgio 1 , Paolo Frezzotti 2 , Ilaria Motolese 2 , Eduardo Motolese 2 , Antonio Federico 1 , and Nicola De Stefano 1
1
Department of Medicine, Surgery and
Neuroscience, University of Siena, Siena, Siena, Italy,
2
Department
of Surgery, Ophthalmology Unit, University of Siena,
Siena, Siena, Italy
By using a multimodal MRI approach, this study
demonstrates in patients with advanced primary open
angle glaucoma (POAG) the presence of structural and
functional changes that go well beyond the visual
system, thus providing evidence that POAG can be
considered a vision disorder belonging to the group of
neurodegenerative conditions and, as such, spreading
throughout the brain
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