Abstract #0128
What are the blood T1 and T2 values in neonates?
Peiying Liu 1 , Lina Chalak 2 , Lisa Krishnamurthy 1 , Imran Mir 2 , Shin-Lei Peng 1 , Hao Huang 1 , and Hanzhang Lu 3
1
Advanced Imaging Research Center, University
of Texas Southwestern Medical Center, Dallas, Texas,
United States,
2
Department
of Pediatrics, University of Texas Southwestern Medical
Center, Texas, United States,
3
University
of Texas Southwestern Medical Center, Dallas, Texas,
United States
Knowledge of blood T1 and T2 is of major importance in
many applications of MRI in neonates. T1 and T2
relaxometry of neonatal blood is different from that of
adult, because of their differences in hemoglobin
molecular structure. Using healthy cord blood samples,
we established a comprehensive relationship between
hematocrit, oxygenation and neonatal blood T1/T2. We
found that neonatal blood has a longer T1 and T2
comparing to adult blood. The neonatal blood T1 and T2
characteristics reported in this work may serve as a
useful reference for future in vivo studies aiming to
assess hemodynamic function in neonates.
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