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Abstract #0130

Delta relaxation enhanced magnetic resonance (dreMR) imaging of a healthy mouse for determination of spin-lattice relaxation rates and R 1 dispersion at 1.5 T

Yonathan T. Araya 1 , Francisco M. Martinez-Santiesteban 1 , Chad T. Harris 2 , William B. Handler 3 , Blaine A. Chronik 3,4 , and Timothy J. Scholl 1,4

1 Medical Biophysics, Western University, London, ON, Canada, 2 Synaptive Medical, Toronto, ON, Canada, 3 Physics and Astronomy, Western University, London, ON, Canada, 4 Robarts Research Institute, Western University, London, ON, Canada

Spin-lattice relaxation rates ( R 1 ) and its associated dispersion over a range of magnetic field shifts (Δ B 0 ) provide useful quantitative tools to differentiate normal and abnormal tissues. We present preliminary imaging results for whole-body R 1 and R 1 dispersion maps of 0.11 T magnetic field shifts about 1.5 T at 37 o C for a healthy mouse using delta relaxation enhanced magnetic resonance (dreMR) imaging. The findings demonstrate unenhanced tissues exhibit little magnetic field dependence about 1.5 T.

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