Abstract #0131
Hunting the Source of a Unique Negative fMRI Signal in the Striatum Using Optogenetics
Daniel Albaugh 1 , Garret Stuber 2 , and Yen-Yu Ian Shih 3
1
Curriculum in Neurobiology, University of
North Carolina at Chapel Hill, Chapel Hill, North
Carolina, United States,
2
Department
of Psychiatry, University of North Carolina at Chapel
Hill, Chapel Hill, North Carolina, United States,
3
BRIC,
Department of Neurology, University of North Carolina at
Chapel Hill, Chapel Hill, North Carolina, United States
Neurovascular coupling represents a central tenet of
functional MRI research. However, in the rodent
striatum, the directionality of vascular responses to
neural activity is not always clear. Here, we employ
optogenetic-fMRI to uncover two striatal circuit
mechanisms of activity-induced vasoconstriction.
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