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Abstract #0165

A Non-Invasive Method for Measuring Perfusion in Moyamoya disease with Functional Magnetic Resonance Imaging

Tianyi Qian 1 , Zhiwei Zuo 2 , Yituo Wang 2 , Yuanyuan Kang 3 , Penggang Qiao 2 , and Gongjie Li 2

1 MR Collaborations NE Asia, Siemens Healthcare, Beijing, Beijing, China, 2 Radiology, Affiliated hospital of Academy of Military Medical Sciences, Beijing, China, 3 Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China

Moyamoya disease (MMD) is deļ¬ned in angiography as a chronic progressive steno-occlusion of internal carotid arteries with characteristically abnormal vascular networks at the base of the brain. In this study, by analyzing the rs-fMRI data with the iteration algorithm described in this paper, the perfusion deficit areas that had long TTP value could be detected non-invasively. The results of our technique match well with TTP maps from DSC-MR and could be a good alternative for monitoring long-term changes of cerebral blood flow pattern in MMD frequently.

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