Hemodynamics of the cerebral border zone regions in healthy, young volunteers
Sophie Schmid 1 , Wouter Teeuwisse 1 , Hanzhang Lu 2 , and Matthias van Osch 1
Radiology, Leiden University Medical Center,
Leiden, Zuid-Holland, Netherlands,
Southwestern Medical Center, Dallas, Texas, United
In this study we employed Time encoded (aka. Hadamard
encoded) pseudo Continuous Arterial Spin Labeling
combined with T2-Relaxation-Under-Spin-Tagging to
evaluate the hemodynamics of the posterior and middle
cerebral artery border zone regions in the brains of
healthy, young volunteers. A significantly lower CBF was
found in the border region compared with the central
region in both the posterior and MCA flow territory. The
arterial transit time in the border zone is
significantly longer compared to the central region.
However, the exchange of the label from the arterial to
the tissue compartment appears to be at a similar rate.
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