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Abstract #0194

Interleaved Acquisition of a Radial Projection Based AIF with a Multi-slice DCE Experiment

Jen Moroz 1 , Andrew Yung 1 , Piotr Kozlowski 2,3 , and Stefan Reinsberg 1

1 Physics and Astronomy, UBC, Vancouver, BC, Canada, 2 Radiology, UBC, Vancouver, BC, Canada, 3 MRI Research Centre, UBC, Vancouver, BC, Canada

This study investigates the potential for interleaving a DCE-MRI experiment with the acquisition of a high temporal resolution AIF using a radial projection-based approach. A mouse tail phantom was scanned with two slice packs: one for the AIF (radial, single slice) and one for the DCE experiment (Cartesian, multi-slice). By interleaving these acquisitions, we maintain a high temporal resolution for the AIF, and sufficient spatial and temporal resolutions for the DCE experiment. This technique is expected to improve the accuracy of fitted model parameters as the AIF is specific to the individual study.

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